NFco-loading® Liposome:
NFco-loading® Liposome is an advanced liposomal delivery technology developed to improve the bioavailability, stability, and absorption of both hydrophilic and lipophilic ingredients. Using ginsenosides instead of cholesterol as membrane stabilizers enables the co-encapsulation of multiple active ingredients with different properties in a single liposomal carrier.
Unlike conventional liposomes that encapsulate a single ingredient, NFco-loading® enables multiple active compounds to be integrated into one liposomal carrier. This approach helps synchronize delivery and supports synergistic formulation design.
NFco-loading® Technology – Efficient Co-Delivery for Complex Formulations
NFco-loading® Technology uses phospholipid vesicles to carry multiple active ingredients with different properties within a single synchronized delivery system. It helps improve formulation synergy, ingredient protection, and absorption efficiency for next-generation nutraceutical and wellness products.
Encapsulates water- and fat-soluble actives in a defined ratio within a single liposomal system to improve delivery efficiency and formulation performance.
Rare ginsenosides are used as functional membrane materials to help protect active ingredients, improve stability, and support stronger synergistic performance.
Using rare ginsenosides (such as Rg3, Rh2, and Rk1) to replace cholesterol, forming a more stable and safer liposomal bilayer structure.
Compared with conventional liposomes, the co-loading liposomes help improve absorption and significantly enhance bioavailability.
Enables rare ginsenosides and other active ingredients to work synergistically within one liposomal delivery system, helping enhance overall functional performance.
Suitable for capsules, powders, liquids, sachets, and a wide range of functional nutrition applications.
Industry-Recognized Liposomal Co-Loading Platform
NFco-loading® Liposomal Curcumin
Gold Winner - Natural Ingredients
CPHI 2025
NFco-loading® Liposomal Coenzyme Q10
Cardiovascular Health Award
VERY FOOD 2025
Co-loading Liposomes
White Paper
Download our White Paper to explore the comprehensive research and learn how to maximize the effectiveness of your active ingredients.
Advanced NFco-loading® Liposomal Ingredient Series
To demonstrate the delivery potential of NFlipo®, our liposomal ingredients were evaluated against their conventional forms in comparative Caco-2 cell studies, tested at 50 μM, 100 μM, and 150 μM.
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NFco-loading® liposomal Curcumin
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NFco-loading® liposomal Coenzyme Q10
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NFco-loading® liposomal NMN
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NFco-loading® Liposomal Curcumin
The results of the Caco-2 cell in vitro absorption simulation experiment show that the relative absorption of Liposomal Curcumin is about 3 times higher that of free Curcumin, and the NFco-loading® Liposomal Curcumin is 8.08 times higher that of free Curcumin.
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NFco-loading® Liposomal Coenzyme Q10
Under the experimental conditions of giving an equal amount of samples, the average relative biological absorption rate of NFco-loading® Coenzyme Q10 is 160% of the Control Coenzyme Q10 sample, suggesting that the in vivo oral absorption rate of NFco-loading® Coenzyme Q10 is higher.
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NFco-loading® Liposomal NMN
Under the experimental conditions of giving an equal amount of samples, the average relative biological absorption rate of NFco-loading® NMN is 157% of the Control NMN sample, suggesting that the in vivo oral absorption rate of NFco-loading® NMN is higher.
Solutions for Multiple Health Applications
Built on NFco-loading® liposomal technology, NF TriSolve® is a scientifically validated formulation platform designed to support multi-active ingredient delivery.
NF TriSolve® Anti-Aging Solution
NF TriSolve® MitoAge Complex is a multi-active liposomal anti-aging formula designed for multifaceted benefits, including antioxidant protection, hydration, and skin brightening. It combines four functional actives in one system:
Partnering to Accelerate Liposomal Product
Commercialization
See how we drive nutraceutical and wellness brands' innovative concepts to market-ready products and accelerate product development with NFco-loading® liposomal technology platform, integrated R&D systems, and scalable manufacturing capabilities.
Flexible Multi-Active Design
Enable hydrophilic and lipophilic actives to work together in one advanced delivery system, with customizable parameters such as particle size, density, appearance, and solubility.
Differentiated Product Positioning
Develop private-label multi-active liposomal supplements backed by 39+ invention patents and trusted by 10,000+ brands across 80+ countries and regions.
Scalable Manufacturing Capability
Support smooth scale-up from concept validation to commercial production with 100+ tons annual manufacturing capacity, CNAS-certified quality testing, and international standards including ISO 9001, HACCP, Halal, and Kosher.
Faster Formulation Commercialization
Speed up product development with integrated co-loading liposomal formulation, pilot-scale testing, and in-house manufacturing support across three specialized R&D and production bases.
Certified for Global Compliance
Our products are certified to international standards, including ISO 9001, HACCP, Halal, and Kosher, supporting compliance and global market access.
Frequently Asked Questions
Q1: How is co-loading liposomal technology different from liposomal technology?
Q2: Can you develop custom co-loaded formulations?
A: Yes. We offer full OEM support and contract manufacturing for co-loaded liposomal ingredients and finished formulations, including R&D development, stability testing, scale-up production, specification control, and documentation support for international markets.
Q3: How do you ensure the quality and stability of your formulas?
A: Each batch is tested for particle size distribution, encapsulation efficiency, stability under storage conditions, and microbiological limits. Together, these controls help ensure consistent quality, stable structure, and reliable performance across production.
Q4: What is the typical MOQ for co-loaded liposomal ingredients?
A: MOQ depends on formulation complexity and development stage. For some products, trial or custom orders start from 1 kg, while regular bulk orders usually start from 25 kg.
Q5: Can samples be provided before the bulk order?
A: Yes. Samples can be provided for testing and formulation evaluation before commercial production.
Q6 :Do you support international shipping and documentation?
A: We support payment methods like T/T and L/C, etc., and provide standard export packaging and required documentation for international delivery.
Ready to Develop Your Co-Loading Liposomal Ingredient Project?
Connect with Natural Field's technical team to discuss your formulation needs, request samples, or get the right technical documentation.
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